Conference program Molecular Biophysics
21-23 March 2024, Kloster Hünfeld, Germany

• 4.30 p.m.

  Opening: Welcome address

• 4.35 p.m. - 5.35 p.m.

  Membranes and bio-constructs

  Ana Garcia-Saez, Köln, GER: Illuminating mitochondrial permeabilization in apoptosis
  Laidy Alvero-Gonzalez, Castellón, Spain: The electrophysiological activity of Dynorphin A reveals both pore formation and neuropeptide translocation regulated by lipid charge
  Darya Radziuk, Minsk, Belarus: Improving NSAIDs: Oxidised Metallographene-NSAID Nanoparticles

• 6.00 p.m.

  Dinner

• 7.30 p.m. - 9.00 p.m.

  Structures & methodologies

  Aneika Leney, Birmingham, UK: Using mass spectrometry as a tool to study the evolution of photosynthesis
  Sarah Harris, Leeds, UK: From genes to machines - multiscale modelling of biomolecular dynamics
  Arwen Pearson, Hamburg, GER: Time-resolved structural biology for the masses: making a niche method part of the routine structural biology toolkit

• 9.00 a.m. - 10.30 a.m.

  Protein-DNA systems

  Alice Pyne, Sheffield, UK: Unravelling the invisible complexities of the genome
  Christian Hearing, Würzburg, GER: Insights into the molecular machines that fold genomes
  Michael Schlierf, Dresden, GER: Molecular mechanisms of the bacterial integron revealed with single molecule biophysics

• 10.30 a.m. - 11.00 a.m.

  Coffee break

• 11.00 a.m. - 12.00 a.m.

  Single molecule dynamics I

  Neil Kad, Kent, UK: Super-resolving the activity of muscle myosins in the native milieu of myofibrils
  Lukas Pekarek, Würzburg, GER: Decoding SARS-CoV-2 frameshifting: Unraveling the orchestrated interplay of RNA Structures
  Annita Jannasch, Tübingen, GER: Superpower behaviour of the budding yeast kinesin-8

• 12.00 a.m.

  Lunch

• 2.00 p.m. - 3.45 p.m.

  Single molecule dynamics II

  George Heath, Leeds, UK: Structural dynamics of single proteins by High-Speed AFM
  Dagmar Klostermeier, Münster, GER: Regulation of topoisomerase activities through modulation of their conformational space and dynamics
  Richard Börner, Mittweida, GER: FRET-guided integrative modelling: A workflow for RNA tertiary contact prediction
  David Rueda, Imperial College London, UK:  FANCD2-FANCI is a sliding clamp that surveys dsDNA and recognizes ssDNA gaps

• 3.45 p.m. - 3.55 p.m.

  Industry Talk: Lumicks B.V.

• 3.55 p.m. - 4.10 p.m.

  Coffee break (20 min.)

• 4.10 p.m.

  Group photo

• 4.15 p.m. - 6.00 p.m.

  Single molecule methodologies

  Stefan Hell, Göttingen/Heidelberg, GER: MINFLUX nanoscopy and related matters
  Don Lamb, LMU Munich, GER: Refolding of discontinuous two-domain protein: A multi-color FRET story
  Yulia Yancheva, Groningen, NL: Investigating the mechanisms of enhanced enzyme diffusion using mass photometry
  Yujia Qing, Oxford, UK: Towards nanopore proteomics: single-molecule analysis of post-translational modifications within full-length proteins

• 6.00 p.m.

  Dinner

• 7.30 p.m. - 7.40 p.m.

  Industry Talk: Molecular Machines & Industries

• 7.40 p.m. - Open end

  Poster Session

• 9.00 a.m. - 10:30 a.m.

  Molecular adhesion

  Seraphine Wegner, Münster, GER: Photoswitchable cell-cell adhesions
  Sergi Garcia-Manyes, King’s College London, UK: Talin oxidation regulates cellular mechanotransduction
  Janine-Denise Kopicki, Hamburg/Siegen, GER: MHC class I peptide screening using native MS
  Alida Meyer, Aachen, Germany: Design and characterization of a FRET based drought sensor utilizing Late Embryogenesis Abundant (LEA) Proteins

• 10.30 a.m. - 11.00 a.m.

  Coffee break

• 11.00 a.m. - 12.00 a.m.

  Viral interactions

  Reidun Twarock, York, UK: Viral geometry as a key to understanding viral infections
  Nivedita Dutta, Poznan, Poland: Modulation of structure and thermodynamics of RNA G-quadruplexes by A and I editing: Possible root to G-quadruplex-based RNA therapeutics
  Fatema-Aqila Said, Hamburg, Germany: The kinetics of SARS-CoV-2 nsp7-11 polyprotein processing and impact on complexation with nsp16

• 12:00 a.m.

  Lunch

• 1.30 p.m. - 2.45 p.m.

  Protein aggregation

  Edward Lemke, Mainz, GER: Decoding Molecular Plasticity in the Dark Proteome
  Henrike Heise, Jülich/Düsseldorf, GER: Protein unfolding and aggregation at all stages as seen by NMR-spectroscopy

• 2.45 p.m. - End

  Concluding words and poster prizes