Cellular biophysics analyses life processes at the level of organelles and whole cells.
Cellular biophysics is a branch of biophysics that focuses on the physical principles of cellular function. It performs a bridging function, starting from the atomic or molecular understanding of proteins, membranes and polynucleotides to the highly complex and highly integrated systems of organelles and whole cells. Finally, the study of tissues and organs ties in with medical biophysics.
Current subfields of cellular biophysics include intracellular signalling dynamics and transport, cell mechanics, molecular motors and electrophysiology. The field has benefited greatly from recent advances in live cell imaging, which allow spatial and temporal measurement of macromolecules and their function. The control of cellular processes by light (optogenetics) also provides unique opportunities to study physiological processes. The combination of novel experimental tools with mathematical models is a particular strength of this field. Advances in cellular biophysics offer new starting points for complex medically relevant questions.
Section III of the DGfB provides a platform for discussion and collaboration in the field of cellular biophysics. The biennial Section Meeting is particularly suitable for this purpose, attracting international biophysicists and researchers from related disciplines. The last Section Meeting, entitled "Mechanobiology in Evolution", was held in Heidelberg from 4-6 July 2022. The next meeting is planned for 2024.