PhD Position in Super-resolution RNA Imaging
Genetically encodable fluorescence markers for imaging of specific RNA molecules in live
cells are still very limited. Within the project ‘Super‐resolution RNA Imaging with Aptamer‐
PAINT’, funded by the Baden‐Württemberg Stiftung (collaboration with the Jäschke lab,
IPMB, U Heidelberg), we will develop advanced light‐up RNA aptamers for live‐cell superresolution
localization microscopy applications.
We are looking for an excellent, highly motivated person with a degree in (bio)physics,
physical chemistry or related fields who is interested in working in an interdisciplinary team
and who is strongly committed to careful biophysical experimentation (single molecule
imaging) and computer‐based quantitative data acquisition and analysis.
Institute of Applied Physics, KIT, 76131 Karlsruhe
Wirth, R.; Gao, P., Nienhaus, G. U., Sunbul, M. and Jäschke, A.
SiRA: A Silicon Rhodamine‐Binding Aptamer for Live‐Cell Super‐Resolution RNA Imaging
J. Am. Chem. Soc. (141), 7562 (2019)